Role of molecular tumor profiling in cancer diagnosis and treatment
Cancer is one of the leading causes of death worldwide, and 1 in 3 people develop cancer once in their lifetime. The global cancer incidence has risen to 18 million in 2018, with the number of people who have died because of cancer in the same year being close to 9.5 million. Unfortunately, these numbers are rising rapidly and are estimated to go higher as the years go by. Multiple factors contribute to rising cancer incidence rates. Such factors are heredity, ageing, exposure to chemicals, as well as other lifestyle and dietary habits like lack of physical activity, high body mass, excessive tobacco and alcohol use.
There has been a dramatic acceleration in the pace of biological research in recent years due to rapid technological and scientific advancements. Combined with the completion of the Human Genome Project, this has enabled the collection and analysis of information that greatly contributed to the understanding of genetic factors and their effect on human life. Identifying the specific genetic alterations that are associated with the development of certain diseases like cancer is crucial in the pursuit of an effective treatment. To find the most effective solution for any disease, a clear understanding of what exactly is responsible for its development is needed. The one-size-fits-all approach adopted in previous years for treating cancer has proved to be ineffective – as there can be no standard treatment for a disease characterized by diversity.
Every person is different, with unique genome variations, traits and characteristics and such is the case with cancer. Every tumor consists of unique genetic mutations that contribute to cancer growth. The same cancer type can be caused by different genetic alterations; subsequently, a tailored approach should be adopted to treat each cancer based on its distinct molecular characteristics. Molecular tumor profiling, a highly technical laboratory genetic test can identify the specific genetic alterations implicated in cancer growth and thus identify treatments that target these specific mutations. “Precision medicine” is the new frontier in cancer patient care. It is a term often used to describe the ability to tailor treatments to an individual patient’s tumor, based on the unique characteristics of their disease, for selecting the optimal treatment.
The information obtained through molecular profiling enables doctors to provide treatment that specifically targets genetic mutations identified to be the cause of the disease. The knowledge gained by tumor profile testing allows for a more accurate and reliable prognosis and helps the healthcare provider choose the most appropriate treatment for their patients, depending on the tumor’s unique genetic characteristics. Thus, the chances of effective treatment increase considerably and consequently, ineffective treatments can be avoided.
Expansion of our knowledge and understanding about cancer and cancer diversity, helps us discover and reevaluate treatments that ultimately could lead to declining cancer incident rates and mortality rates all together.
Compiled using information from:
Press Release No 263, Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018, World Health Organization, International Agency for Research on Cancer, 2018 [https://www.who.int/cancer/PRGlobocanFinal.pdf]
HONORARY RECOGNITION FOR PROFESSOR PHILIPPOS PATSALIS AT THE RESEARCH & INNOVATION AWARDS 2022
Cyprus Employers & Industrialists Federation (OEB) recognized Professor Philippos Patsalis for his highly significant contribution to the development and provision of innovative products and methodologies …
NIPD Genetics is a leading, innovative biotechnology company that designs, develops, and provides a
broad spectrum of healthcare services to its customers through its expansive portfolio of molecular
and clinical laboratory tests in all disciplines.
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NIPD Genetics collects and processes your personal information according to the General Data
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persons with regards to the processing of personal data and for the free movement of such data (L.
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Lawfulness, fairness and transparency – We collect and process personal data in a lawful
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Purpose limitation – We only use personal data for the purpose for which they have been
Data minimization – We only collect the data that is absolutely necessary in relation to
purposes for which they are processed.
Accuracy – We take every reasonable step to ensure that personal data collected are
and up to date.
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periodically reviewed and erased if they are not needed or anonymized and stored for scientific
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and promote internal practices to achieve the highest standards for personal data privacy.
NIPD Genetics has appointed a Data Protection Officer (DPO) who is responsible for overseeing and
ensuring that personal information is collected and processed in line with these principles. The contact
details of the Data Protection Officer (DPO) can be found below:
Postal address: 31 Neas Engomis street, 2409 Engomi, Nicosia, Cyprus
Telephone number: + 357 22266888
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you do not agree with our policies, procedures and practices as described, you can choose not to
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We collect and process several types of personal information from and about users of our websites
and of our products and services, including:
Personal and sensitive information: some of our products and services may involve testing
biological samples that we or our customers use to create test reports, genotyping or sequencing
services for research or clinical purposes and the receipt, creation, or analysis of genomic or other
data derived from samples, including through our customer’s use of our software as a service
product. In receiving samples and providing our products and services, we may obtain your name
and surname, date of birth, email address, home address, telephone number, gender, ethnicity
and other health related information.
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information about your computer or device, as well as browsing actions and usage patterns. This
data may include your IP address, browser type or version.
The technologies we use for this automatic data collection may include cookies. You can control
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If you are under 18 years of age, do not register on our website or provide any information about
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their personal information. Despite this prohibition, it is possible that we may sometimes be given
information about children while handling samples from our customers in our clinical labs, or through
use of our products and services by our customers and partners. If we become aware that we have
inadvertently collected personal information from children under the age of 18, without parental
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Your personal information is collected by NIPD Genetics for the following purposes:
To provide you with our products and services, respond to your inquiries or fulfill your requests
and otherwise manage your relationship with us. The legal basis for processing is to meet the
requirements of a contract, to comply with our legal obligations and/or because we have a
legitimate interest in responding to requests for information about our products and services.
To communicate with you about content and product offerings, newsletters and event invitations
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To monitor and record information relating to the use of our products and services, including our
website. The legal basis for processing is our legitimate interest in order to improve our products
and services and our website for individuals.
To provide our products and services, NIPD Genetics may collect, receive and process biological
samples to isolate and sequence DNA. NIPD Genetics may then store resulting genetic information
and use genetic information to provide our products and services. In some cases, NIPD Genetics may
provide interpretations of genetic information on behalf of its customers, including healthcare
providers. This is only done pursuant to a written contract or a Sample Information Form with a
patient’s informed consent and is subject to applicable legal and ethical safeguards.
This sensitive information described above is collected by NIPD Genetics for the following purposes:
To provide support and maintenance services to customers who use our products and services –
The legal basis for processing is to meet the requirements of a contract.
To provide genotyping and sequencing services and analysis for our customers, including
healthcare providers. The legal basis of this processing is to meet the requirements of a contract
or as allowed in the Sample Information Form with a patient’s informed consent.
To conduct genotyping and sequencing services and analysis for quality control, process and
product development and improvements, and optimization in our labs to reflect quality
improvements and advances in our technology. The legal basis for processing is the patient’s
informed consent given through the Sample Information Form.
Transfer of Data
Your information, including personal data, may be transferred to - and maintained on - computers
located outside your province, country or other governmental jurisdiction where the data protection
laws may differ than those from your jurisdiction.
If you are located outside Cyprus and choose to provide information to us, please note that we transfer
the data, including personal data, to Cyprus and process it there.
agreement to that transfer.
NIPD Genetics will take all reasonable steps necessary to ensure that your data is treated securely and
an organization or a country unless there are adequate controls in place including the security of your
data and other personal information.
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NIPD Genetics complies with the General Data Protection Regulation and will not sell or trade your
NIPD Genetics may disclose your personal information in the good faith that such action is necessary:
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To protect against legal liability
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certain information. This includes information about the computer or device you are using, such as
Internet protocol (IP) address, information about the browser type or version, the pages of our
website that you visit, the time and date of your visit, the time spent on those pages, unique device
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if you do not accept cookies, you may not be able to use some portions of our websites.
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We may use third-party Service Providers to monitor and analyze the use of our websites.
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Google uses the data collected to track and monitor the use of our service. This data is shared with
other Google services. Google may use the collected data to contextualize and personalize the ads of
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You can opt-out of having made your activity on the Service available to Google Analytics by installing
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For more information on the privacy practices of Google, please visit the Google Privacy & Terms web
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We are committed to protecting the security of the information we collect, and we take reasonable
physical, technical, and administrative safeguards such as data anonymization and encryption to help
protect personal information from unauthorized or inappropriate access or use. It is your
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PERSONAL DATA RETENTION
We may retain collected information even after you remove it from the website, our Services, or our
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personal information varies depending on the purpose for its use and we may delete or retain your
personal information in accordance with applicable law.
We may employ third party companies and individuals to facilitate, maintain or operate our websites
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assist us in analyzing how our websites are used.
These third parties have access to your Personal Data only to perform these tasks on our behalf and
are obligated not to disclose or use it for any other purpose.
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Our websites may contain links to other sites that are not operated by us. If you click on a third-party
of every site you visit.
We have no control over and assume no responsibility for the content, privacy policies or practices of
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We will let you know via email and/or a prominent notice on our website, prior to the change
are effective when they are posted on this page.
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NIPD Genetics ensures that it can respond immediately to requests that you make for the exercise of
your legal rights in accordance with data protection laws. These rights are as follows:
The right to withdraw consent at any time – in cases where processing is based on your
The right of access – at any given time you have the right to know what information about you
we hold and receive information about the processing activities we perform
The right to rectify – you have the right to correct, amend and complete personal data that is
The right to erasure (“right to be forgotten”) – you can request that your personal information
The right to object – you can object at any time to our processing of your personal information
The right to restriction of processing – this applies in the event:
You dispute the accuracy of your personal information and until it is verified
You oppose to the deletion of personal data and ask instead to delete the use of it
The personal information is no longer necessary for us
You object to the processing and we are considering whether our legitimate grounds
for processing prevail over the reasons you oppose to the processing
The right to data portability – at any given time you have the right to receive the personal
information we hold about you in a structured, commonly used and machine-readable format
(pdf, word etc.). You also have the right to request that these data are transferred to another
service in a safe and secure way
You also have the right to lodge a complaint at any time to the Office of the Commissioner for Personal
We encourage you to contact us, should you wish to practice any of your legal rights or you have any