WHAT IS Rodinia?

Rodinia is a genetic test for infertility that screens for mutations in individuals who have difficulty achieving pregnancy. By identifying genetic variants associated with infertility and disorders of sex chromosomes, Rodinia can provide accurate prognostic assessment and identify the most applicable treatment options for each patient. Rodinia can help guide you towards an optimal treatment plan for any couple or individual wishing to have a child.


Rodinia offers a Female and a Male Infertility Panel. Each panel detects ​ numerous genetic variants associated with infertility. Rodinia also detects whole,​ partial and mosaic sex chromosome changes.

In addition, Rodinia provides a Thrombophilia and NAIT Panel that could be​ offered either as an Add-on to the Female or Male Panel, or as a Stand-alone Panel.


55 genes, X chromosome aneuploidies

Screens for genetic variants associated with female infertility and includes disorders such as primary ovarian insufficiency, polycystic ovary syndrome, ovarian hyperstimulation syndrome and hypogonadotropic hypogonadism disorders such as Kallman syndrome.

Early interventions to preserve fertility: Early identification of women with primary ovarian insufficiency can determine the need for oocyte harvesting and cyropreservation at a young age to preserve fertility and enable the patient to have a child in the future.


40 genes, X and Y chromosome aneuploidies, including Y-chromosome microdeletions

Screens for genetic variants that can cause male factor inferitlity, including sex chromosome changes and hypogonadotropic hypogonadism disorders like Kallman syndrome.

Prognostic value for treatment: Azoospermic men have a higher prevalence of microdeletions on the Y-chromosome than men with normal sperm and should receive genetic testing to clarify etiology prior to treatment*. Of the 3 deletions that are associated with azoospermia, only one is associated with a chance of recovering sperm through testicular sperm extraction treatment (TESE).


22 genetic variants

Checks for specific genetic variants associated with recurrent pregnancy loss. Can be offered​ to couples or individuals that have had more than one miscarriage, or have a family history of ​ Neonatal Alloimmune Thrombocytopenia (NAIT), among other reasons.

Can be selected as an Add-on Panel to the Female or Male Panel, or as a Stand-alone Panel.​

Guidance on treatment decisions:​ Identifying variants associated with recurrent​ pregnancy loss can determine the need for​ taking treatment, such as hormonal therapy​ or anticoagulants, which may reduce or​ prevent complications during pregnancy and​ delivery. ​

*Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile male: a committee opinion (2015)

For a complete list of the genes and diseases tested by Rodinia, please visit nipd.com/rodiniapanel

WHO IS Rodinia FOR?

Couples or individuals experiencing pregnancy delay
Individuals with specific phenotype indicating a genetic syndrome associated with a sex chromosome aneuploidy
Females with irregular or absent menstruation
Males with low sperm count, irregular sperm form, or movement
Any individual or couple that will undergo assisted reproductive technology (ART) treatment
Candidates for sperm or oocyte donation
Individuals with family history of infertility
Couples or individuals ​with more than one miscarriage​
Applicable only for the Thrombophilia & NAIT panel​


Biochemical and instrumental testing, such as hormone checks, ultrasounds and semen analysis can identify up to 65% of infertility cases. If the cause of infertility remains undetermined, genetic testing can be offered as a significant number of infertility cases are attributed to genetic variants.

Up to 15% of men and up to 10% in women have a genetic mutation which is linked with infertility. Genetic testing can provide deep insight that acts as a valuable prognostic tool, and can guide you to take informed and accurate decisions on the best clinical management and treatment for your patient. Genetic testing could subsequently help increase the patient's chances for achieving a pregnancy.


Thoroughly validated target capture enrichment technology

X and Y chromosome analysis for whole copy number changes, and partial changes down to 10Mb

Mosaicism detection in sex chromosomes down to 15%

Full coverage of all coding regions, detecting single nucleotide variants, small insertions and deletions, and copy number variants

The Thrombophilia & NAIT panel targets specific variants​

Novel bioinformatics for high sensitivity and specificity


  • Results on mutations tested
  • Thorough interpretation and clinical significance of variants detected
  • Reporting pathogenic and likely pathogenic variants, and variants of uncertain significance

Carrier status will not be reported for recessive conditions.​
The Thrombophilia & NAIT panel reports the genotype​ for the variants tested.


By identifying the underlying genetic cause of infertility, Rodinia can help you to:

Determine accurate prognosis for your patient

Evaluate and choose the most optimal treatment for your patient

Manage clinical care by being aware of potential complications, like ovarian hyperstimulation

Advice your patient on how to proceed with pregnancy planning

Recommend testing to family members, if applicable


Infertility is considered a major disorder of the reproductive system and it affects approximately 1 in 6 couples worldwide.

Rodinia uses robust and proven technology to detect mutations on genes associated with infertility and changes on sex chromosomes. Rodinia can provide important insight regarding the reproductive health of an individual and guide treatment options to help them achieve conception.

Early detection of the underlying genetic cause of infertility can act as a prognostic tool and be pivotal to the choice and outcome of treatment. Early detection can also determine the need for earlier interventions at a younger age, to preserve fertility.

Rodinia provides invaluable genetic insight which can guide you to create a more personalized approach for family planning for each couple or individual.


Superior targeted genomic analysis

Identifies genetic mutations associated with infertility

Guides patient-specific clinical management and treatment

Enables accurate prognosis

Easy to interpret results

High precision and accuracy

†Agarwal A., et al., 'A unique view on male infertility around the globe'. Reproductive biology and endocrinology, 2015.



NIPD Genetics - Privacy Policy

General Statement

NIPD Genetics is a leading, innovative biotechnology company that designs, develops, and provides a broad spectrum of healthcare services to its customers through its expansive portfolio of molecular and clinical laboratory tests in all disciplines.

At NIPD Genetics we are committed to protecting and respecting our customer’s privacy and personal information. Personal information or personal data means any information that identifies, relates to, describes, is capable of being associated with, or could be reasonably linked, directly or indirectly, with a particular individual, such as name, identification number, location data, an online identifier or to one or more factors specific to the physical, physiological, genetic, mental, economic, cultural or social identity of that individual.

NIPD Genetics collects and processes your personal information according to the General Data Protection Regulation (EU) 2016/679 and the Cypriot law providing for the protection of natural persons with regards to the processing of personal data and for the free movement of such data (L. 125(I)/2018). The following principles lie at the heart of our approach to handling personal data:

NIPD Genetics has appointed a Data Protection Officer (DPO) who is responsible for overseeing and ensuring that personal information is collected and processed in line with these principles. The contact details of the Data Protection Officer (DPO) can be found below:

Email address: dpo@nipd.com

Postal address: 31 Neas Engomis street, 2409 Engomi, Nicosia, Cyprus

Telephone number: + 357 22266888

By accessing or using our products or services, or by transmitting information to us by email or other electronic means, you accept our policies, procedures and practices described in this Privacy Policy. If you do not agree with our policies, procedures and practices as described, you can choose not to access or use our products or services or not to transmit personal information to us.

This Privacy Policy applies to NIPD Genetics facilities, its websites www.nipd.com, www.nipdlabs.com, www.nipdlabs.com.cy and their subdomains, that link to this privacy pol icy.


We collect and process several types of personal information from and about users of our websites and of our products and services, including:

Information about children

If you are under 18 years of age, do not register on our website or provide any information about yourself to us. We do not provide our products or services directly to children or proactively collect their personal information. Despite this prohibition, it is possible that we may sometimes be given information about children while handling samples from our customers in our clinical labs, or through use of our products and services by our customers and partners. If we become aware that we have inadvertently collected personal information from children under the age of 18, without parental consent, we will take the necessary steps to delete it as soon as possible in compliance with applicable laws.


Your personal information is collected by NIPD Genetics for the following purposes:

  1. To provide you with our products and services, respond to your inquiries or fulfill your requests and otherwise manage your relationship with us. The legal basis for processing is to meet the requirements of a contract, to comply with our legal obligations and/or because we have a legitimate interest in responding to requests for information about our products and services.
  2. To communicate with you about content and product offerings, newsletters and event invitations which are relevant to your interests and in line with your preferences. The legal basis for processing is the individual’s explicit consent prior to sending the information and managing individuals preferences.
  3. To process and respond to complaints. The legal basis for processing is to meet a legal obligation.
  4. To monitor and record information relating to the use of our products and services, including our website. The legal basis for processing is our legitimate interest in order to improve our products and services and our website for individuals.

To provide our products and services, NIPD Genetics may collect, receive and process biological samples to isolate and sequence DNA. NIPD Genetics may then store resulting genetic information and use genetic information to provide our products and services. In some cases, NIPD Genetics may provide interpretations of genetic information on behalf of its customers, including healthcare providers. This is only done pursuant to a written contract or a Sample Information Form with a patient’s informed consent and is subject to applicable legal and ethical safeguards.

This sensitive information described above is collected by NIPD Genetics for the following purposes:

  1. To provide support and maintenance services to customers who use our products and services – The legal basis for processing is to meet the requirements of a contract.
  2. To provide genotyping and sequencing services and analysis for our customers, including healthcare providers. The legal basis of this processing is to meet the requirements of a contract or as allowed in the Sample Information Form with a patient’s informed consent.
  3. To conduct genotyping and sequencing services and analysis for quality control, process and product development and improvements, and optimization in our labs to reflect quality improvements and advances in our technology. The legal basis for processing is the patient’s informed consent given through the Sample Information Form.

Transfer of Data

Your information, including personal data, may be transferred to - and maintained on - computers located outside your province, country or other governmental jurisdiction where the data protection laws may differ than those from your jurisdiction.

If you are located outside Cyprus and choose to provide information to us, please note that we transfer the data, including personal data, to Cyprus and process it there.

Your consent to this Privacy Policy followed by your submission of such information represents your agreement to that transfer.

NIPD Genetics will take all reasonable steps necessary to ensure that your data is treated securely and in accordance with this Privacy Policy and no transfer of your personal information will take place to an organization or a country unless there are adequate controls in place including the security of your data and other personal information.

Disclosure of Data

NIPD Genetics complies with the General Data Protection Regulation and will not sell or trade your personal information.

NIPD Genetics may disclose your personal information in the good faith that such action is necessary:


Cookies are files with small amount of data which may include an anonymous unique identifiers. Cookies are sent to your browser when you visit a website and stored on your device. Tracking technologies used on the website are beacons, tags and scripts, to collect and track information and to improve and analyze our websites.

We use cookies and similar tracking technologies to track the activity on our websites and collect certain information. This includes information about the computer or device you are using, such as Internet protocol (IP) address, information about the browser type or version, the pages of our website that you visit, the time and date of your visit, the time spent on those pages, unique device identifiers and other diagnostic data.

You can instruct your browser to refuse all cookies or to indicate when a cookie is being sent. However, if you do not accept cookies, you may not be able to use some portions of our websites.

Examples of Cookies we may use:

Session Cookies. We use Session Cookies to operate our websites.

Preference Cookies. We use Preference Cookies to remember your preferences and various settings.

Security Cookies. We use Security Cookies for security purposes.

Visitor behavior cookies. To understand how visitors use and navigate the websites

Keyword cookies. To understand how visitors discover the websites.


We may use third-party Service Providers to monitor and analyze the use of our websites.

Google Analytics

Google Analytics is a web analytics service offered by Google that tracks and reports website traffic. Google uses the data collected to track and monitor the use of our service. This data is shared with other Google services. Google may use the collected data to contextualize and personalize the ads of its own advertising network.

You can opt-out of having made your activity on the Service available to Google Analytics by installing the Google Analytics opt-out browser add-on. The add-on prevents the Google Analytics JavaScript (ga.js, analytics.js, and dc.js) from sharing information with Google Analytics about visits activity.

For more information on the privacy practices of Google, please visit the Google Privacy & Terms web page


We are committed to protecting the security of the information we collect, and we take reasonable physical, technical, and administrative safeguards such as data anonymization and encryption to help protect personal information from unauthorized or inappropriate access or use. It is your responsibility to protect the confidentiality of your passwords, and any other access features associated with your access or use of the website or our products and services, as well as to adhere to any applicable Terms of Use or other contract between us and you or your organization.


We may retain collected information even after you remove it from the website, our Services, or our Products, to comply with applicable law, to resolve disputes, to enforce any rights in connection with the website, our Services, or our Products, and to use as provided in this Privacy Policy, the Terms of Use, or an applicable contract between us and you or your organization. How long we retain specific personal information varies depending on the purpose for its use and we may delete or retain your personal information in accordance with applicable law.


We may employ third party companies and individuals to facilitate, maintain or operate our websites (“Service Providers”), to provide the websites on our behalf, to perform service-related services or to assist us in analyzing how our websites are used.

These third parties have access to your Personal Data only to perform these tasks on our behalf and are obligated not to disclose or use it for any other purpose.


Our websites may contain links to other sites that are not operated by us. If you click on a third-party link, you will be directed to that third party's site. We strongly advise you to review the Privacy Policy of every site you visit.

We have no control over and assume no responsibility for the content, privacy policies or practices of any third-party sites or services.


This Privacy Policy may be updated from time to time. We will notify you of any changes by posting the new Privacy Policy on this page.

We will let you know via email and/or a prominent notice on our website, prior to the change becoming effective and update the “effective date” at the bottom of this Privacy Policy.

You are advised to review this Privacy Policy periodically for any changes. Changes to this Privacy Policy are effective when they are posted on this page.


NIPD Genetics ensures that it can respond immediately to requests that you make for the exercise of your legal rights in accordance with data protection laws. These rights are as follows:

You also have the right to lodge a complaint at any time to the Office of the Commissioner for Personal Data Protection.

We encourage you to contact us, should you wish to practice any of your legal rights or you have any questions about this Privacy Policy, by sending an email to NIPD Genetics’ Data Protection Officer at dpo@nipd.com.

Effective date: 18/06/2021

Ok got it!