WHAT IS Amfira PGT?
Amfira is a preimplantation genetic test (PGT) that can help you increase your chances of becoming pregnant and delivering a healthy baby. Amfira can be used during In Vitro Fertilization (IVF) cycles to test embryos and detect which ones are chromosomally normal (euploid). Euploid embryos have the highest potential of resulting in a successful pregnancy and delivery of a healthy baby.
HOW DOES Amfira PGT HELP ME?
Chromosomal changes (aneuploidies) are the primary cause of miscarriages during pregnancy. Whole chromosome aneuploidies occur more frequently with increasing maternal age. Women over 35 years old generally have more difficulty conceiving, a higher risk of miscarriage and of having a baby with a chromosomal abnormality. However, other types of aneuploidies, like segmental changes or mosaicism (mix of normal and abnormal cells), can occur in women of all ages.
Euploid embryos have the best potential for implanting and leading to a healthy pregnancy, with as few IVF cycles as possible, as euploid embryos are preferentially transferred over others that may not have the same reproductive potential.
By identifying euploid embryos, Amfira PGT can help you take informed decisions about your pregnancy and optimize your chances of a successful and healthy live birth.
WHO SHOULD HAVE Amfira PGT?
WHY SHOULD I ASK MY DOCTOR ABOUT Amfira PGT?
PGT cannot correct embryos with a chromosomal aneuploidy. It can only identify which embryos have aneuploidies and which don't. With Amfira PGT, your embryologist will confidently know which embryos are euploid and select them for transfer, which could:
- Increase chances of a successful pregnancy
- Increase chances of healthy live births
- Lower miscarriage rate
- Lead to safer pregnancies by promoting single embryo transfers (SET), thus avoiding complications of multiple pregnancy
- Achieve a pregnancy earlier than in cycles without PGT
WHAT WILL Amfira PGT TELL ME?
Amfira will let you know whether your embryos are:
Euploid: An embryo which is chromosomally normal, having in total 46 chromosomes. Euploid embryos have the best chance of implantation, successful pregnancy and birth of a healthy baby.
Aneuploid: An embryo with additional or fewer chromosomes than the correct number. Depending on whether a whole chromosome is missing or is extra, or just a part of it (segmental aneuploidy), the survival, implantation rate, risk of miscarriage and the health of the baby are affected.
Mosaic: An embryo which has the correct number of chromosomes in some of its cells, and an incorrect number of chromosomes in others. Your fertility team may choose to implant a mosaic embryo, depending on the chromosome affected by mosaicism and whether there are no euploid embryos available.
Amfira OFFERS 2 PGT PANELS:
PGT-A: PGT for Aneuploidies
For all individuals or couples going through IVF.
PGT-A examines the chromosomes of embryos to detect the ones that are euploid and have the best prospect to result in a healthy pregnancy. PGT-A tests for all 23 chromosomal pairs.
A person with a balanced translocation may have:
- Difficulty conceiving
- Recurrent pregnancy loss
- A child without the translocation, or with a balanced form of the translocation, who will be phenotypically healthy
- A child with an unbalanced form of the translocation that will have extra or missing chromosomal material, which may cause physical or intellectual impairements
IS PGT THE BEST CHOICE FOR ME?
In the last two decades, PGT has become a routine part of IVF cycles. PGT requires embryo biopsy to be performed during IVF; which is a procedure many experienced embryologists are trained to perform. During the procedure, a few cells from the developing embryo are removed and sent to our laboratory for testing, while the embryos remain in the fertility clinic. Overall, treatment success, both in terms of higher live birth rates and lower miscarriage rates, is improved when PGT is used as part of the IVF cycle. Obstetric, neonatal and early childhood outcome data in children conceived through IVF and PGT are reassuring. With the continuing advancements of technology, the latest techniques both in embryo biopsy and preimplantation genetic testing provide highest levels of safety, efficiency and accuracy than ever before.
The graph above shows the advantage of identifying and transferring a euploid embryo, where one exists, in regards to live births.
✝ Data obtained from the Preliminary National Summary Report for 2018 of the Society for Assisted Reproductive Technology (SART) and summarize data per transfer for first embryo transfers using patients' own eggs.
HOW IS Amfira PGT PERFORMED?
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- Type of personal information NIPD Genetics may collect through its Sites
- The ways by which NIPD Genetics collects, uses or shares such information
- Steps NIPD Genetics takes to protect its sites’ users personal information
This page informs you of our policies regarding the collection, use, and disclosure of personal data when you use our Sites and the choices you have associated with that data.
Type of personal information NIPD Genetics may collect through its Sites
Information Collection And Use
We collect several different types of information for various purposes to provide and improve our Sites and services to you.
While using NIPD Genetics Sites, you may be asked to provide NIPD Genetics certain personally identifiable information that can be used to contact or identify you ("Personal Information"). Personal Information that might be used to identify you includes, but is not limited to:
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If you send us a query via our Contact us form, your email address, the content and any follow up emails are retained indefinitely.
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We may also collect information how the Sites are accessed and used ("Usage Data"). This Usage Data may include information such as your computer's Internet Protocol address (e.g. IP address), browser type, browser version, the pages of our Sites that you visit, the time and date of your visit, the time spent on those pages, unique device identifiers and other diagnostic data.
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Cookies are files with small amount of data which may include an anonymous unique identifier. Cookies are sent to your browser from a website and stored on your device. Tracking technologies also used are beacons, tags, and scripts to collect and track information and to improve and analyze our Sites.
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Examples of Cookies we use:
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www.nipd.com uses the collected data for various purposes:
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- To monitor the usage of the Sites
- To detect, prevent and address technical issues
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Your information, including personal data, may be transferred to — and maintained on — computers located outside of your province, country or other governmental jurisdiction where the data protection laws may differ than those from your jurisdiction.
If you are located outside Cyprus and choose to provide information to us, please note that we transfer the data, including personal data, to Cyprus and process it there.
Disclosure of Data
NIPD Genetics complies with the protection of personal data regulation and will not sale or trade your personal data.
NIPD Genetics may disclose your personal data in the good faith belief that such action is necessary to:
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Security of Data
The security of your data is important to us, but remember that no method of transmission over the Internet, or method of electronic storage is 100% secure. While we strive to use commercially acceptable means to protect your Personal Data, we cannot guarantee its absolute security.
We may employ third party companies and individuals to facilitate, maintain or operate our Sites ("Service Providers"), to provide the SItes on our behalf, to perform service-related services or to assist us in analyzing how our Sites is used.
These third parties have access to your Personal Data only to perform these tasks on our behalf and are obligated not to disclose or use it for any other purpose.
We may use third-party Service Providers to monitor and analyze the use of our Sites.
Google Analytics is a web analytics service offered by Google that tracks and reports website traffic. Google uses the data collected to track and monitor the use of our Service. This data is shared with other Google services. Google may use the collected data to contextualize and personalize the ads of its own advertising network.
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Links to Other Sites
We have no control over and assume no responsibility for the content, privacy policies or practices of any third-party sites or services.
Our Service does not address anyone under the age of 18 ("Children").
We do not knowingly collect personally identifiable information from anyone under the age of 18. If you are a parent or guardian and you are aware that your Children has provided us with Personal Data, please contact us. If we become aware that we have collected Personal Data from children without verification of parental consent, we take steps to remove that information from our servers.