WHAT IS Adventia CARRIER SCREENING?

Adventia is a new genetic test for carrier screening to determine whether a phenotypically healthy person is a carrier of a genetic disease. The genetic insight provided by Adventia can inform, guide and empower people on their reproductive choices and minimize the risk of people who are carriers transmitting a genetic disease to their children. Adventia offers a choice of different panels and testing for up to 229 moderate to severe autosomal recessive and X-linked genetic diseases.

Adventia Panels

1

FOCUS PANELS

Six individual panels for high frequency and severe genetic diseases: A-Thalassemia, B-Haemoglobinopathies, Cystic Fibrosis, Duchenne Muscular Dystrophy, Fragile X, Spinal Muscular Atrophy.

View More

19

GUIDELINES-BASED PANEL

Single panel that detects 19 genetic diseases recommended by international genetic organizations like ACMG and ACOG* due to their high incidence and severity. The Guidelines Based panel includes all diseases tested in the Focus panels, and other diseases including Phenylketonuria, Fanconi Anemia Group C and Tay-Sachs disease.

View More

229

COMPREHENSIVE PANEL

Single panel for 229 diseases that have moderate to severe, well-defined phenotype and high cumulative frequency. The Comprehensive panel includes all diseases of the Guidelines Based panel, and covers a wide range of metabolic, cardiovascular, haematological, muscular, immunological, neurological and pulmonary diseases amongst others.

View More

Adventia, TESTING BEYOND ETHNICALLY-PREVALENT DISEASES
Ethnicity-based carrier screening only tests for a very limited number of diseases and may leave individuals who are multiracial or unaware of their ethnic or genetic background undiagnosed. While there are certain diseases that are more prevalent in some populations, due to genetic diversity and migration, an expanded carrier screening test offers comprehensive and unbiased information.

WHY RECOMMEND Adventia Carrier Screening?

Adventia tests for autosomal recessive and X-linked diseases which:

  • have moderate to severe phenotype
  • are high in carrier frequency
  • can compromise quality of life
  • may be manageable through early interventions

*American College of Medical Genetics and Genomics, American College of Obstetrics and Gynecologists

WHO IS ADVENTIA CARRIER SCREENING FOR?

Couples planning to start their families and want to know about their carrier status
Any individual or couple going through assisted reproduction, including IVF
Sperm and oocyte donors, and recipients of sperm or oocyte donation
Couples who are already pregnant and want to know whether their child has a risk of having a genetic disease
High-risk population groups for specific diseases
People with a family history of a genetic mutation
Any individual wishing to know more about their genetic background

WHEN SHOULD MY PATIENTS GET TESTED?

Adventia carrier screening can be done by any individual or couple when they wish to learn more about their genetic information to minimize the risk of transmitting a genetic disease to their children. Adventia can also be done during pregnancy if prospective parents wish to know whether their child has a risk of having a genetic disease.

ROBUST TECHNOLOGICAL DESIGN

TARGETED TECHNOLOGY

Adventia carrier screening is based on a novel, target capture enrichment technology that has been thoroughly validated for its accuracy and precision.

FULL COVERAGE

Adventia screens for all coding regions on the genes of interest, increasing the chances of identifying any pathogenic or likely pathogenic mutations: single nucleotide variants, small insertions and deletions, and copy number variants.

NOVEL BIOINFORMATICS

Innovative bioinformatics pipelines analyze the sequencing data produced from each sample, increasing the sensitivity and specificity of Adventia carrier screening.

WHAT DOES THE REPORT LOOK LIKE?

reports-image

POSITIVE OR NEGATIVE RESULTS ON MUTATIONS TESTED

THOROUGH INTERPRETATION AND SIGNIFICANCE OF POSITIVE MUTATIONS IDENTIFIED

WHAT CAN I DO AFTER Adventia CARRIER SCREENING?

Depending on the results, the disease, and whether the test was performed by an individual wanting to know more about their genetic profile or a couple planning their family, there are multiple choices you can recommend to your patients:

  • Genetic counseling to receive more information on the potential impact of the disease, and discuss their choices on how to minimize the risk of transmitting the disease to their children
  • Having prenatal diagnosis during pregnancy, if they wish to know whether their baby is affected or not
  • Choosing in-vitro fertilization (IVF) and preimplantation genetic testing (PGT-M) if they want to make sure their baby will not have the affected phenotype
  • Choosing a compatible gamete donor without the same mutation
  • Early intervention, therapies where available and better clinical management for affected children

Adventia CARRIER SCREENING

  • Genetic insight about patient’s carrier status
  • Testing for moderate to severe diseases which can severely affect quality of life, health and development
  • Minimize transmission of genetic diseases to offspring
  • Comprehensive report with meaningful results
  • Reproductive planning
  • Powerful technology
  • Short turn-around time
  • Safe and easy to perform

WHY OFFER CARRIER SCREENING TO MY PATIENTS?

Anyone can be a carrier of recessive mutations and pass them to the next generation without their knowledge. A recessive disease manifests only when a child inherits a pathogenic mutation from both parents. Without carrier screening, asymptomatic carriers of recessive mutations often discover their carrier status only after they have an affected child.

  • Knowledge of an individual’s genetic profile can help them understand their risk of transmitting a genetic disease to their children, and evaluate their reproductive options to prevent that risk.
  • Genetic diseases may be rare with varying prevalence but can have adverse effects on health and development, or be life-threatening.
  • Early knowledge about diseases that can be clinically manageable, like metabolic disorders, can result in earlier intervention, therapies where available and better clinical management for affected children.

International genetic organizations like the American College of Obstetricians and Gynecologists (ACOG), and the American College of Medical Genetics and Genomics (ACMG) recommend that carrier screening for the most serious and prevalent genetic diseases is offered to everyone planning to start a family. Several professional organizations like the National Society of Genetic Counselors (NSGC), Perinatal Quality Foundation and Society for Maternal-Fetal-Medicine (SMFM) also agree that carrier screening information should be provided to all pregnant women.

DISEASE CARRIER FREQUENCY POPULATION
Cystic fibrosis 1 in 45 General population
Alpha thalassemia 1 in 25 General Population
Beta thalassemia 1 in 28 Mediterranean
Spinal muscular atrophy 1 in 35 Caucasian
CUMULATIVE FREQUENCY
1 in 4 people is a carrier of a genetic disease
Lazarin et al., 2013

HOW TO ADMINISTER Adventia CARRIER SCREENING?

  • DISCUSS Adventia WITH YOUR PATIENT
  • COLLECT A CHEEK SWAB FROM YOUR PATIENT
  • SEND THE SAMPLE TO OUR LABORATORY
  • THE SAMPLE WILL BE ANALYZED IN OUR LABORATORY
  • RESULTS WILL BE SENT TO YOU WITHIN 2-3 WEEKS

NIPD Genetics - Privacy Policy

General Statement

NIPD Genetics is a leading, innovative biotechnology company that designs, develops, and provides a broad spectrum of healthcare services to its customers through its expansive portfolio of molecular and clinical laboratory tests in all disciplines.

At NIPD Genetics we are committed to protecting and respecting our customer’s privacy and personal information. Personal information or personal data means any information that identifies, relates to, describes, is capable of being associated with, or could be reasonably linked, directly or indirectly, with a particular individual, such as name, identification number, location data, an online identifier or to one or more factors specific to the physical, physiological, genetic, mental, economic, cultural or social identity of that individual.

NIPD Genetics collects and processes your personal information according to the General Data Protection Regulation (EU) 2016/679 and the Cypriot law providing for the protection of natural persons with regards to the processing of personal data and for the free movement of such data (L. 125(I)/2018). The following principles lie at the heart of our approach to handling personal data:

NIPD Genetics has appointed a Data Protection Officer (DPO) who is responsible for overseeing and ensuring that personal information is collected and processed in line with these principles. The contact details of the Data Protection Officer (DPO) can be found below:

Email address: dpo@nipd.com

Postal address: 31 Neas Engomis street, 2409 Engomi, Nicosia, Cyprus

Telephone number: + 357 22266888

By accessing or using our products or services, or by transmitting information to us by email or other electronic means, you accept our policies, procedures and practices described in this Privacy Policy. If you do not agree with our policies, procedures and practices as described, you can choose not to access or use our products or services or not to transmit personal information to us.

This Privacy Policy applies to NIPD Genetics facilities, its websites www.nipd.com, www.nipdlabs.com, www.nipdlabs.com.cy and their subdomains, that link to this privacy pol icy.

PERSONAL INFORMATION COLLECTION AND PROCESSING

We collect and process several types of personal information from and about users of our websites and of our products and services, including:

Information about children

If you are under 18 years of age, do not register on our website or provide any information about yourself to us. We do not provide our products or services directly to children or proactively collect their personal information. Despite this prohibition, it is possible that we may sometimes be given information about children while handling samples from our customers in our clinical labs, or through use of our products and services by our customers and partners. If we become aware that we have inadvertently collected personal information from children under the age of 18, without parental consent, we will take the necessary steps to delete it as soon as possible in compliance with applicable laws.

LEGAL BASIS FOR PROCESSING OF YOUR PERSONAL INFORMATION

Your personal information is collected by NIPD Genetics for the following purposes:

  1. To provide you with our products and services, respond to your inquiries or fulfill your requests and otherwise manage your relationship with us. The legal basis for processing is to meet the requirements of a contract, to comply with our legal obligations and/or because we have a legitimate interest in responding to requests for information about our products and services.
  2. To communicate with you about content and product offerings, newsletters and event invitations which are relevant to your interests and in line with your preferences. The legal basis for processing is the individual’s explicit consent prior to sending the information and managing individuals preferences.
  3. To process and respond to complaints. The legal basis for processing is to meet a legal obligation.
  4. To monitor and record information relating to the use of our products and services, including our website. The legal basis for processing is our legitimate interest in order to improve our products and services and our website for individuals.

To provide our products and services, NIPD Genetics may collect, receive and process biological samples to isolate and sequence DNA. NIPD Genetics may then store resulting genetic information and use genetic information to provide our products and services. In some cases, NIPD Genetics may provide interpretations of genetic information on behalf of its customers, including healthcare providers. This is only done pursuant to a written contract or a Sample Information Form with a patient’s informed consent and is subject to applicable legal and ethical safeguards.

This sensitive information described above is collected by NIPD Genetics for the following purposes:

  1. To provide support and maintenance services to customers who use our products and services – The legal basis for processing is to meet the requirements of a contract.
  2. To provide genotyping and sequencing services and analysis for our customers, including healthcare providers. The legal basis of this processing is to meet the requirements of a contract or as allowed in the Sample Information Form with a patient’s informed consent.
  3. To conduct genotyping and sequencing services and analysis for quality control, process and product development and improvements, and optimization in our labs to reflect quality improvements and advances in our technology. The legal basis for processing is the patient’s informed consent given through the Sample Information Form.

Transfer of Data

Your information, including personal data, may be transferred to - and maintained on - computers located outside your province, country or other governmental jurisdiction where the data protection laws may differ than those from your jurisdiction.

If you are located outside Cyprus and choose to provide information to us, please note that we transfer the data, including personal data, to Cyprus and process it there.

Your consent to this Privacy Policy followed by your submission of such information represents your agreement to that transfer.

NIPD Genetics will take all reasonable steps necessary to ensure that your data is treated securely and in accordance with this Privacy Policy and no transfer of your personal information will take place to an organization or a country unless there are adequate controls in place including the security of your data and other personal information.

Disclosure of Data

NIPD Genetics complies with the General Data Protection Regulation and will not sell or trade your personal information.

NIPD Genetics may disclose your personal information in the good faith that such action is necessary:

COOKIES AND OTHER TRACKING TECHNOLOGIES

Cookies are files with small amount of data which may include an anonymous unique identifiers. Cookies are sent to your browser when you visit a website and stored on your device. Tracking technologies used on the website are beacons, tags and scripts, to collect and track information and to improve and analyze our websites.

We use cookies and similar tracking technologies to track the activity on our websites and collect certain information. This includes information about the computer or device you are using, such as Internet protocol (IP) address, information about the browser type or version, the pages of our website that you visit, the time and date of your visit, the time spent on those pages, unique device identifiers and other diagnostic data.

You can instruct your browser to refuse all cookies or to indicate when a cookie is being sent. However, if you do not accept cookies, you may not be able to use some portions of our websites.

Examples of Cookies we may use:

Session Cookies. We use Session Cookies to operate our websites.

Preference Cookies. We use Preference Cookies to remember your preferences and various settings.

Security Cookies. We use Security Cookies for security purposes.

Visitor behavior cookies. To understand how visitors use and navigate the websites

Keyword cookies. To understand how visitors discover the websites.

ANALYTICS

We may use third-party Service Providers to monitor and analyze the use of our websites.

Google Analytics

Google Analytics is a web analytics service offered by Google that tracks and reports website traffic. Google uses the data collected to track and monitor the use of our service. This data is shared with other Google services. Google may use the collected data to contextualize and personalize the ads of its own advertising network.

You can opt-out of having made your activity on the Service available to Google Analytics by installing the Google Analytics opt-out browser add-on. The add-on prevents the Google Analytics JavaScript (ga.js, analytics.js, and dc.js) from sharing information with Google Analytics about visits activity.

For more information on the privacy practices of Google, please visit the Google Privacy & Terms web page

SECURITY OF DATA

We are committed to protecting the security of the information we collect, and we take reasonable physical, technical, and administrative safeguards such as data anonymization and encryption to help protect personal information from unauthorized or inappropriate access or use. It is your responsibility to protect the confidentiality of your passwords, and any other access features associated with your access or use of the website or our products and services, as well as to adhere to any applicable Terms of Use or other contract between us and you or your organization.

PERSONAL DATA RETENTION

We may retain collected information even after you remove it from the website, our Services, or our Products, to comply with applicable law, to resolve disputes, to enforce any rights in connection with the website, our Services, or our Products, and to use as provided in this Privacy Policy, the Terms of Use, or an applicable contract between us and you or your organization. How long we retain specific personal information varies depending on the purpose for its use and we may delete or retain your personal information in accordance with applicable law.

SERVICE PROVIDERS

We may employ third party companies and individuals to facilitate, maintain or operate our websites (“Service Providers”), to provide the websites on our behalf, to perform service-related services or to assist us in analyzing how our websites are used.

These third parties have access to your Personal Data only to perform these tasks on our behalf and are obligated not to disclose or use it for any other purpose.

LINKS TO OTHER SITES

Our websites may contain links to other sites that are not operated by us. If you click on a third-party link, you will be directed to that third party's site. We strongly advise you to review the Privacy Policy of every site you visit.

We have no control over and assume no responsibility for the content, privacy policies or practices of any third-party sites or services.

CHANGES TO THIS PRIVACY POLICY

This Privacy Policy may be updated from time to time. We will notify you of any changes by posting the new Privacy Policy on this page.

We will let you know via email and/or a prominent notice on our website, prior to the change becoming effective and update the “effective date” at the bottom of this Privacy Policy.

You are advised to review this Privacy Policy periodically for any changes. Changes to this Privacy Policy are effective when they are posted on this page.

YOUR LEGAL RIGHTS

NIPD Genetics ensures that it can respond immediately to requests that you make for the exercise of your legal rights in accordance with data protection laws. These rights are as follows:

You also have the right to lodge a complaint at any time to the Office of the Commissioner for Personal Data Protection.

We encourage you to contact us, should you wish to practice any of your legal rights or you have any questions about this Privacy Policy, by sending an email to NIPD Genetics’ Data Protection Officer at dpo@nipd.com.

Effective date: 18/06/2021

Ok got it!